Sei Yoshida’s Lab in Nankai University
Our lab is studying the molecular mechanism and the physiological/pathological relevance of the PI3K-AKT-mTORC1 pathway in the context of longevity.
The main research directions are:
1. Role of macropinocytosis, large-scale endocytosis, in AKT activation.
2. Role of the interaction of macropinocytosis-mTORC1 pathway in cancer development.
3. Role of macropinocytosis in podocyte, kidney epithelial cell.
The extensive breadth and diversity in our research areas (cell biology, biochemistry, nephrology, microbiology, and immunology) enable us to make momentous contributions to the understanding of human health and disease.
Contact us freely if you are interested in our projects!
Related Links
·Role of Circular Dorsal Ruffles in Hepatocelluar carcinoma. CCS (2022).
·Bacteria tear down microtubules.
·Growth factor signal transduction through dorsal ruffles. JCS(2018).
·Bacterial Bushwacking Through a Microtubule Jungle. Science(2006).
·On the cover: Endoplasmic reticulum–associated degradation in podocytes.
Lab Party Time
